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Shigeru Kinoshita Selected Research

gelatinous drop-like Corneal dystrophy

7/2019Clinical outcomes and time to recurrence of phototherapeutic keratectomy in Japan.
1/2019A novel mutation in gelatinous drop-like corneal dystrophy and functional analysis.
1/2015Novel TACSTD2 mutation in gelatinous drop-like corneal dystrophy.
8/2013Establishment of a human corneal epithelial cell line lacking the functional TACSTD2 gene as an in vitro model for gelatinous drop-like dystrophy.
6/2013Classification of secondary corneal amyloidosis and involvement of lactoferrin.
12/2012Establishment of a human conjunctival epithelial cell line lacking the functional TACSTD2 gene (an American Ophthalmological Society thesis).
4/2011Two novel mutations of TACSTD2 found in three Japanese gelatinous drop-like corneal dystrophy families with their aberrant subcellular localization.
9/2010Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy.
3/2007Phenotypic investigation of cell junction-related proteins in gelatinous drop-like corneal dystrophy.

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Shigeru Kinoshita Research Topics

Disease

44Stevens-Johnson Syndrome (Lyell's Syndrome)
01/2022 - 10/2002
34Dry Eye Syndromes (Dry Eye Syndrome)
02/2021 - 01/2002
30Inflammation (Inflammations)
02/2021 - 02/2003
20Glaucoma
01/2022 - 09/2002
13Cataract (Cataracts)
01/2017 - 10/2002
12Infections
11/2018 - 06/2004
10Keratitis
11/2018 - 10/2002
9Myopia
09/2021 - 02/2004
9gelatinous drop-like Corneal dystrophy
07/2019 - 03/2007
9Wounds and Injuries (Trauma)
11/2018 - 09/2003
8Allergic Conjunctivitis (Giant Papillary Conjunctivitis)
05/2021 - 02/2009
8Neoplasms (Cancer)
01/2019 - 03/2010
7Fuchs' Endothelial Dystrophy
10/2021 - 08/2013
7Refractive Errors (Refractive Error)
12/2020 - 03/2003
7Open-Angle Glaucoma (Glaucoma, Open Angle)
09/2020 - 03/2006
7Hypersensitivity (Allergy)
01/2019 - 02/2004
6Macular Degeneration (Age-Related Maculopathy)
05/2022 - 09/2002
6Astigmatism
09/2021 - 08/2010
6Cicatrix (Scar)
11/2020 - 08/2004
6Keratoconjunctivitis
01/2017 - 03/2003
5Hereditary Corneal Dystrophies
11/2020 - 07/2010
5Macular Edema
11/2018 - 08/2005
5Sarcoidosis (Schaumann Disease)
11/2017 - 06/2005
5Corneal Edema
09/2015 - 11/2005
4Exfoliation Syndrome
01/2021 - 06/2007
4Blister (Bulla)
12/2020 - 08/2004
4Corneal Opacity
11/2020 - 04/2004
4Uveitis
11/2017 - 06/2005
4Polypoidal Choroidal Vasculopathy
06/2014 - 11/2011
3Fibrosis (Cirrhosis)
12/2021 - 06/2006
3Pterygium
01/2021 - 06/2006
3Keratoconus
01/2021 - 01/2002
3Blindness (Hysterical Blindness)
11/2020 - 07/2006
3Eye Infections
01/2020 - 01/2013
3Endophthalmitis (Ophthalmia)
01/2020 - 01/2011
3Corneal Neovascularization
12/2017 - 05/2005
3Virus Diseases (Viral Diseases)
11/2017 - 07/2007
3Contact Dermatitis (Eczema, Contact)
11/2017 - 02/2014
3Corneal Injuries
03/2016 - 04/2004
3Asthma (Bronchial Asthma)
01/2016 - 05/2008
3Edema (Dropsy)
11/2014 - 11/2002
3Eye Burns (Eye Burn)
08/2014 - 01/2011
3Diabetic Retinopathy (Retinopathy, Diabetic)
10/2012 - 01/2003
3Benign Mucous Membrane Pemphigoid (Cicatricial Pemphigoid)
01/2012 - 11/2005
3Ulcer
01/2011 - 09/2003

Drug/Important Bio-Agent (IBA)

24Ophthalmic Solutions (Eye Drops)IBA
10/2021 - 04/2006
15Proteins (Proteins, Gene)FDA Link
05/2022 - 08/2005
12CytokinesIBA
11/2020 - 02/2003
10Retinaldehyde (Retinal)IBA
05/2022 - 08/2003
10Fluorescein (Funduscein)FDA LinkGeneric
02/2021 - 11/2003
8rebamipideIBA
01/2021 - 12/2012
8Pharmaceutical PreparationsIBA
01/2020 - 04/2004
8HLA-A Antigens (HLA-A)IBA
01/2017 - 04/2002
7Toll-Like Receptor 3IBA
02/2021 - 07/2007
7Anti-Bacterial Agents (Antibiotics)IBA
01/2021 - 04/2012
7HLA-B Antigens (HLA-B)IBA
01/2019 - 11/2008
7SteroidsIBA
09/2015 - 12/2002
6HLA Antigens (Human Leukocyte Antigens)IBA
01/2022 - 04/2002
6CalciumIBA
01/2019 - 03/2010
6Latanoprost (Xalatan)FDA Link
01/2016 - 09/2002
5K-115IBA
01/2021 - 11/2015
5Biomarkers (Surrogate Marker)IBA
11/2020 - 11/2013
5EP3 Subtype Prostaglandin E ReceptorsIBA
01/2020 - 12/2010
5DNA (Deoxyribonucleic Acid)IBA
11/2017 - 09/2003
5Interleukin-8 (Interleukin 8)IBA
01/2014 - 04/2004
4LipidsIBA
10/2022 - 12/2008
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2022 - 12/2012
4AntigensIBA
01/2022 - 02/2015
4Mitomycin (Mitomycin-C)FDA LinkGeneric
01/2021 - 06/2006
4rho-Associated KinasesIBA
01/2021 - 01/2012
4Y 27632IBA
09/2015 - 07/2011
4SuspensionsIBA
03/2014 - 11/2002
4Messenger RNA (mRNA)IBA
01/2012 - 04/2006
4Interleukin-6 (Interleukin 6)IBA
09/2004 - 07/2003
3Adrenal Cortex Hormones (Corticosteroids)IBA
11/2021 - 09/2003
3Protein Kinases (Protein Kinase)IBA
10/2021 - 11/2015
3CollagenIBA
12/2020 - 03/2007
3Dinoprostone (PGE2)FDA Link
01/2020 - 11/2012
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2018 - 01/2011
3Toll-Like Receptors (Toll-Like Receptor)IBA
11/2017 - 07/2007
3Immunoglobulin E (IgE)IBA
01/2017 - 08/2008
3Amyloid (Amyloid Fibrils)IBA
08/2013 - 09/2010
3SiliconesIBA
02/2013 - 06/2002
3ProstaglandinsIBA
11/2012 - 02/2009

Therapy/Procedure

21Therapeutics
11/2021 - 06/2002
18Corneal Transplantation (Keratoplasty)
11/2020 - 10/2002
14Transplantation
11/2020 - 06/2004
8Contact Lenses
09/2021 - 06/2006
8Trabeculectomy (Trabeculoplasty)
04/2021 - 08/2004
7Lasers (Laser)
01/2022 - 10/2002
7Penetrating Keratoplasty
01/2021 - 08/2009
5Laser In Situ Keratomileusis (LASIK)
12/2020 - 02/2004
5Punctal Plugs
01/2018 - 06/2002
5Operative Surgical Procedures
03/2016 - 03/2003
4Refractive Surgical Procedures
07/2020 - 12/2015
4Keratectomy
01/2013 - 11/2005
3Slit Lamp
02/2020 - 02/2010
3Sutures (Suture)
01/2020 - 03/2003
3Intraocular Lenses (Intraocular Lens)
06/2015 - 08/2010
3Intravitreal Injections
08/2012 - 01/2011